Laser-induced graphene (LIG) is a promising material for chemical, physical, and physiological sensing. LIG has been used to make proof-of-concept motion, heartbeat, respiration, and voice sensors. These hold the potential to revolutionize physiological parameter sensing, due to their simplicity, versatility, effectiveness and suitability for wearable applications. LIG is usually fabricated by irradiating a polyimide (PI) sheet with a laser, which converts a thin top layer of PI to graphene. However, PI is not optimally biocompatible and flexible, hence LIG is commonly transferred from PI to other polymers. The transfer is often incomplete, resulting in loss of material and damaged devices. We propose to address the integration of LIG with biocompatible polymers synthesized in our lab, finding the optimal host polymer for applications in heartbeat monitoring. We will study the surface, structural and mechanical properties of the devices and their sensing performance. The impact of the project on the field of wearable physiological parameter sensors will be significant, as the projected results are bound to improve the performance of LIG-based sensors and also lower the barriers to adoption of these sensors by the industry.